Improved dropClust R package with integrative analysis support for scRNA-seq data.
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- Record sourced from PubMed, PMID 31693086.
- Also identified by DOI 10.1093/bioinformatics/btz823.
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Abstract
DropClust leverages Locality Sensitive Hashing (LSH) to speed up clustering of large scale single cell expression data. Here we present the improved dropClust, a complete R package that is, fast, interoperable and minimally resource intensive. The new dropClust features a novel batch effect removal algorithm that allows integrative analysis of single cell RNA-seq (scRNA-seq) datasets. dropClust is freely available at https://github.com/debsin/dropClust as an R package. A lightweight online version of the dropClust is available at https://debsinha.shinyapps.io/dropClust/. Supplementary data are available at Bioinformatics online.