From Mother or Father: Uniparental Embryos Uncover Parent-of-Origin Effects in Humans.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31703767.
- Also identified by DOI 10.1016/j.stem.2019.10.007.
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Abstract
In mammals, both parents make unique contributions to the offspring and maternal and paternal genomes are required for development. Two recent papers in Cell Stem Cell (Leng et al., 2019; Sagi et al., 2019) study uniparental embryos and uniparental embryonic stem cells to interrogate parent-of-origin effects in human embryogenesis.
Medical subject headings
- Embryonic Stem Cells
- Fathers