Transformation of Grade II to Grade III Rhabdoid-Papillary Meningioma: Is Stereotactic Radiosurgery the Culprit? A Case Report and Literature Review.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 31715408.
- Also identified by DOI 10.1016/j.wneu.2019.11.019.
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Abstract
In the management of meningiomas, single-fraction stereotactic radiosurgery (SRS) is an established alternative treatment to surgical resection. However, its effects on tumorigenesis and malignant transformation are still uncertain. We have described a grade II parafalcine meningioma that was initially surgically resected (Simpson 2 clearance) and then managed with a single dose of SRS on recurrence. The tumor recurred again 7 years later, with histological features of a grade III rhabdoid-papillary lesion, with local brain invasion. To the best of our knowledge, this is the first report to describe malignant transformation of a grade II to grade III meningioma after SRS to date.
Medical subject headings
- Meningeal Neoplasms
- Meningioma
- Neoplasm Recurrence, Local
- Radiosurgery