Cellular Plasticity in Musculoskeletal Development, Regeneration, and Disease.
review · Level V
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- Record sourced from PubMed, PMID 31721278.
- Also identified by DOI 10.1002/jor.24523 and PMC identifier 7213644.
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Abstract
In this review, we highlight themes from a recent workshop focused on "Plasticity of Cell Fate in Musculoskeletal Tissues" held at the Orthopaedic Research Society's 2019 annual meeting. Experts in the field provided examples of mesenchymal cell plasticity during normal musculoskeletal development, regeneration, and disease. A thorough understanding of the biology underpinning mesenchymal cell plasticity may offer a roadmap for promoting regeneration while attenuating pathologic differentiation. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 38:708-718, 2020.
Medical subject headings
- Cell Plasticity
- Musculoskeletal Development