Association between particulate matter air pollution and lung cancer.

Zhang, Zhenyu; Zhu, Dawei; Cui, Bin; Ding, Ruoxi; Shi, Xuefeng; He, Ping · Thorax · 2020

cross_sectional · Level IV

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Abstract

Long-term exposure to particulate matter 2.5 μm (PM<sub>2.5</sub>) air pollution is associated with an increased risk of lung cancer. However, the evidence is limited in low-income and middle-income countries. We estimated the association between the incidence of lung cancer and PM<sub>2.5</sub> air pollution exposure in the Urban Employee Basic Medical Insurance (UEBMI) beneficiaries in China. A total of 16 483 new lung cancer cases diagnosed from 12 966 137 UEBMI beneficiaries from 36 cities between 2013 and 2016. The relative risk for lung cancer associated with a 10 µg/m<sup>3</sup> increase in 3-year PM<sub>2.5</sub> exposure was 1.12 (95% CI 1.00 to 1.26). The population attributable risk estimated for a reduction in PM<sub>2.5</sub> concentration to 35 µg/m<sup>3</sup> corresponded to a decrease of 14% in cases of lung cancer. Reducing PM<sub>2.5</sub> air pollution has a significant public health benefit.

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