<i>Burkholderia cenocepacia</i> ET12 transmission in adults with cystic fibrosis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 31732688.
- Also identified by DOI 10.1136/thoraxjnl-2019-214098.
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Abstract
This report describes transmission of a <i>Burkholderia cenocepacia</i> ET12 strain (ET12-Bc) at the Toronto Adult Cystic Fibrosis (CF) Centre occurring from 2008 to 2017. Epidemiological and genomic data from 11 patients with CF were evaluated. Isolates were analysed using whole genome sequencing (WGS). Epidemiological investigation and WGS analysis suggested nosocomial transmission, despite enhanced infection control precautions. This was associated with subsequent deaths in 10 patients. ET12-Bc positive patients are no longer cared for on the same unit as ET12-Bc negative patients.
Medical subject headings
- Burkholderia Infections
- Burkholderia cenocepacia
- Cystic Fibrosis