Combining dielectrophoresis and computer vision for precise and fully automated single-cell handling and analysis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31746875.
- Also identified by DOI 10.1039/c9lc00800d.
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Abstract
With the advent of single-cell technologies comes the necessity for efficient protocols to process single cells. We combine dielectrophoresis with open source computer vision programming to automatically control the trajectories of single cells inside a microfluidic device. Using real-time image analysis, individual cells are automatically selected, isolated and spatially arranged.
Medical subject headings
- Electrophoresis
- Lab-On-A-Chip Devices
- Microfluidic Analytical Techniques
- Single-Cell Analysis