Invasive Mold Infections After Chimeric Antigen Receptor-Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 31756246.
- Also identified by DOI 10.1093/cid/ciz1127.
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Abstract
Data on invasive mold infections (IMIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) therapy are limited. We describe 2 patients with post-CAR-T-cell IMI (Fusarium, Mucorales) and review the published literature. We propose strategies to prevent IMIs in patients, based on the IMI rate and presence of neutropenia or steroid use.
Medical subject headings
- Mucorales
- Neutropenia
- Receptors, Chimeric Antigen