Ferric citrate: cardio- and renoprotective in chronic kidney disease?
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 31759486.
- Also identified by DOI 10.1016/j.kint.2019.09.004.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Ferric citrate is a phosphate binder that may also be used to treat iron-deficiency anemia. In human studies, ferric citrate treatment in the setting of chronic kidney disease has been associated with effective phosphate control, improved iron and hematologic parameters, and decreased fibroblast growth factor 23 levels. In the present study, mice with chronic kidney disease treated with ferric citrate have similarly improved biochemical profiles, but also have improved cardiac and renal function and prolonged survival.
Medical subject headings
- Anemia, Iron-Deficiency
- Renal Insufficiency, Chronic