SimRVSequences: an R package to simulate genetic sequence data for pedigrees.

Nieuwoudt, Christina; Brooks-Wilson, Angela; Graham, Jinko · Bioinformatics · 2020

basic_science · Level V

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Abstract

We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample of unrelated individuals. SimRVSequences is publicly-available on CRAN https://cran.r-project.org/web/packages/SimRVSequences/. Supplementary data are available at Bioinformatics online.

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