A CMOS NMR needle for probing brain physiology with high spatial and temporal resolution.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31768059.
- Also identified by DOI 10.1038/s41592-019-0640-3.
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Abstract
Magnetic resonance imaging and spectroscopy are versatile methods for probing brain physiology, but their intrinsically low sensitivity limits the achievable spatial and temporal resolution. Here, we introduce a monolithically integrated NMR-on-a-chip needle that combines an ultra-sensitive 300 µm NMR coil with a complete NMR transceiver, enabling in vivo measurements of blood oxygenation and flow in nanoliter volumes at a sampling rate of 200 Hz.
Medical subject headings
- Brain
- Image Interpretation, Computer-Assisted
- Magnetic Resonance Imaging
- Magnetic Resonance Spectroscopy
- Oxygen