Clinical Characteristics of Active Tuberculosis Diagnosed After Starting Treatment for Latent Tuberculosis Infection.

Flynn, Andrew G; Aiona, Kaylynn; Haas, Michelle K; Reves, Randall; Belknap, Robert · Clin Infect Dis · 2020

retrospective_cohort · Level III

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Abstract

Although rare, subclinical tuberculosis disease can be missed during evaluations for latent tuberculosis infection, and can manifest with symptoms during latent tuberculosis treatment. Among over 8000 patients treated for latent tuberculosis we found no evidence of acquired drug resistance, underscoring the safety of rifampin monotherapy for latent tuberculosis.

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