Modeling the Evolution of Human Brain Development Using Organoids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31778651.
- Also identified by DOI 10.1016/j.cell.2019.10.041 and PMC identifier 7034679.
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Abstract
In a recent issue of Nature, Kanton et al. explore human brain evolution and development by profiling the single-cell transcriptomes and epigenomes of cerebral organoids derived from human, chimpanzee, and macaque stem cells. Their results reveal key molecular characteristics that differentiate humans and non-human primates at the earliest stages of brain development.
Medical subject headings
- Genomics
- Organoids