Characterizing the BCR repertoire in immune-mediated diseases.

Ramadoss, Nitya S; Robinson, William H · Nat Rev Rheumatol · 2020

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Abstract

B cells can assume protective or pathogenic roles in immune-mediated diseases (IMDs). Analysis of the B cell receptor (BCR) repertoires in six IMDs provides insights into the diversity of B cell repertoires across diseases as well as into potential pathological mechanisms and the effects of different treatments.

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