Metastatic Breast Cancer: TIL it is Too Late.

Savas, Peter; Loi, Sherene · Clin Cancer Res · 2020

editorial · Level V

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Abstract

Paired analysis of primary and metastatic triple-negative breast cancers shows that metastatic disease is an immunodepleted state. This understanding has important implications for targeting the immune microenvironment in breast cancer, placing a greater emphasis on earlier stage disease and shaping future treatment strategies in the metastatic setting.<i>See related article by Hutchinson et al., p. 657</i>.

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