OPCs on a Diet: A Youthful Serving of Remyelination.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31801054.
- Also identified by DOI 10.1016/j.cmet.2019.11.009.
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Abstract
Remyelination declines in the aging central nervous system due to oligodendrocyte precursor cell (OPC) dysfunction. In the latest issue of Cell Stem Cell, Neumann et al. (2019) demonstrate that aged OPCs are amenable to functional rejuvenation by systemic interventions involving alternate-day fasting or treatment with the fasting mimetic metformin.
Medical subject headings
- Metformin
- Remyelination