Association of Sex With Toxic Effects, Treatment Adherence, and Oncologic Outcomes in the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trials of Rectal Cancer.

Diefenhardt, Markus; Ludmir, Ethan B; Hofheinz, Ralf-Dieter; Ghadimi, Michael; Minsky, Bruce D; Rödel, Claus; Fokas, Emmanouil · JAMA Oncol · 2020

rct · Level II

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Abstract

This pooled analysis of data from phase 3 randomized clinical trials assesses the association of sex with toxic effects, treatment adherence, surgical procedures, and long-term outcomes after standard multimodal treatment in patients with rectal cancer.

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