Sensing the Environment: Extracellular Lactate Levels Control Adult Neurogenesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 31809733.
- Also identified by DOI 10.1016/j.stem.2019.11.008.
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Abstract
Metabolism has emerged as a key player for stem cell behavior; however, the role of metabolism in the microenvironment remains poorly understood. In this issue of Cell Stem Cell, Wang et al. (2019) show that brain endothelial cells directly affect adult neural stem cells and maintain a healthy metabolic environment by regulating lactate levels.
Medical subject headings
- Endothelial Cells
- Lactic Acid