Outbreak of an Uncommon Rifampin-resistant blaNDM-1Citrobacter amalonaticus Strain in a Digestive Rehabilitation Center: The Putative Role of Rifaximin.

Royer, Guilhem; Fourreau, Fréderic; Gomart, Camille; Maurand, Audrey; Hacquin, Bruno; Ducellier, David; Cizeau, Florence; Lo, Stéphane et al. · Clin Infect Dis · 2020

case_series · Level IV

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Abstract

We describe a sudden 2-week outbreak due to a blaNDM-1Citrobacter amalonaticus strain in a 22-bed digestive rehabilitation center. Three of the 5 colonized patients received long-term rifaximin treatment to prevent hepatic encephalopathy. The strains were genotypically identical, phenotypically resistant to rifampin, and harbored arr-3, a rifampin adenosine diphosphate-ribosyl transferase.

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