Functional heartburn: An underrecognized cause of PPI-refractory symptoms.

Gabbard, Scott; Vijayvargiya, Sonya · Cleve Clin J Med · 2019

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Abstract

Functional heartburn--persistent symptoms of esophageal reflux with no objective evidence of gastroesophageal reflux disease (GERD)--is the most common cause of failure of proton pump inhibitor (PPI) therapy, but it is often overlooked by internists and gastroenterologists.

Medical subject headings