Limited antibody specificity compromises epitranscriptomic analyses.
Level V
Where this comes from
- Record sourced from PubMed, PMID 31827101.
- Also identified by DOI 10.1038/s41467-019-13684-3 and PMC identifier 6906430.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A controversial discussion on the occurrence of the RNA modification m<sup>1</sup>A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.
Medical subject headings
- Antibodies
- Epigenesis, Genetic
- Transcriptome