Poly(ethylene glycol)-poly(vinyl alcohol)-adamantanate: synthesis and stimuli-responsive micelle properties.

Deng, Wei; Chen, Jing; Kulkarni, Aditya; Thompson, David H · Soft Matter · 2012

basic_science · Level V

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Abstract

A pH-sensitive amphiphilic polymer based on poly(vinyl alcohol) (PVA), modified with poly(ethylene glycol) (PEG) and adamantane (Ad) pendant groups, has been synthesized and the self-assembly properties of this PEG-PVA-Ad construct investigated. PEG-PVA-Ad polymer forms micelles <i>via</i> self-assembly at concentrations as low as 26 mg L<sup>-1</sup>. These polymer micelles can be destroyed by low pH or the addition of β-CD.