Splicing Calls Back.

Hoffmann, Tobias; Valcárcel, Juan · Cell · 2019

editorial · Level V

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Abstract

Removal of introns from eukaryotic messenger RNA precursors often occurs co-transcriptionally. In this issue of Cell, Fiszbein et al. report that evolutionary or tissue-specific activation of an internal exon can enhance gene expression by promoting the use of alternative transcription initiation sites.

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