One Prime for All Editing.

Yang, Li; Yang, Bei; Chen, Jia · Cell · 2019

review · Level V

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Abstract

Many targeted base transversions, insertions, and deletions remain challenging due to the lack of precise and efficient genome editing technologies. Recently, Anzalone et al. reported a versatile approach to achieve all types of genome edits, shedding new light on correcting most genetic variants associated with diseases.

Medical subject headings