Over-diagnosis of Rotavirus Infection in Infants Due to Detection of Vaccine Virus.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 31848594.
- Also identified by DOI 10.1093/cid/ciz1196.
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Abstract
An accurate rotavirus diagnosis is important for clinical management and monitoring active disease and vaccine effectiveness. Between 2016-2018, rotavirus-positive results in our laboratory were from vaccine virus shedding in 71/152 (46.7%) infants with a request for rotavirus testing. Routine infant diagnostic testing should ideally distinguish vaccine from wild-type viruses.
Medical subject headings
- Rotavirus
- Rotavirus Infections
- Rotavirus Vaccines