Immune imbalance and activation are associated with lower lung function in youth with perinatally acquired HIV.
Where this comes from
- Record sourced from PubMed, PMID 31874184.
- Also identified by DOI 10.1016/j.jaci.2019.12.890 and PMC identifier 7214131.
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Abstract
High CD8 T-cells and low CD4/CD8 are associated with lower lung function among youth living with perinatally-acquired HIV, despite antiretroviral therapy and CD4 preservation/reconstitution. Understanding these underlying mechanisms is critical to mitigate lung function impairment.
Medical subject headings
- HIV Infections
- Infectious Disease Transmission, Vertical