Study on microstructure, microhardness, bioactivity, and biocompatibility of La<sub>2</sub> O<sub>3</sub> -containing bioceramic coating doping SiO<sub>2</sub> fabricated by laser cladding.
basic_science · Level V
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- Record sourced from PubMed, PMID 31883307.
- Also identified by DOI 10.1002/jbm.b.34548.
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Abstract
To solve the lack of strength of calcium phosphate ceramic coatings in load-bearing applications, gradient Ca-P bioceramic coatings doped with La<sub>2</sub> O<sub>3</sub> and SiO<sub>2</sub> are fabricated by laser cladding on Ti-6Al-4 V. The effect of SiO<sub>2</sub> on microstructure, microhardness, bioactivity, and biocompatibility of coatings was investigated. The experimental results illustrate that the coating doped with La<sub>2</sub> O<sub>3</sub> and SiO<sub>2</sub> has excellent metallurgical bonding. The XRD analysis confirms that the amount of hydroxyapatite and tricalcium phosphate in the coating reached maximum when doping amount of SiO<sub>2</sub> is 10 wt %. SiO<sub>2</sub> -doped coatings show a significantly higher bone-like apatite precipitation after immersion in SBF than that of other coatings. in vitro experiment also shows that coating with 10 wt % SiO<sub>2</sub> is more suitable for the attachment and proliferation of MG63 cells, indicating that coating with 10 wt % SiO<sub>2</sub> exhibits best bioactivity and biocompatibility. These results suggest that the addition of SiO<sub>2</sub> improves the bonding strength, bioactivity, and biocompatibility of coatings.
Medical subject headings
- Calcium Phosphates
- Ceramics
- Coated Materials, Biocompatible
- Lanthanum
- Oxides
- Silicon Dioxide