Two Cases of Interleukin-7-Deficient Generalized Verrucosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 31900472.
- Also identified by DOI 10.1093/cid/ciz1240.
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Abstract
We report 2 generalized verrucosis (GV) patients homozygous for a novel mutation in the start codon of IL7. Unlike the previous report in which IL-7 deficiency accompanied CD4 T lymphocytopenia, circulating CD4 T cells were not depleted in one of our patients, suggesting a GV pathogenesis other than poor T-cell development.
Medical subject headings
- CD4-Positive T-Lymphocytes
- Interleukin-7
- Warts