Enamel Repair with Amorphous Ceramics.

Abstract

Developing high-performance materials in physiological conditions to clinically repair stiff tissue for long lifespan remains a great challenge. Here, an enamel repair strategy is reported by efficiently growing a biocompatible ZrO₂ ceramic layer on defective enamel through controllable hydrolysis of Zr⁴⁺ in oral-tolerable conditions. Detailed analysis of the grown layer indicates that the grown ZrO₂ ceramic is amorphous without grain boundary and dislocation, which endows the repaired enamel with natural enamel comparable mechanical performance (modulus ≈82.5 GPa and hardness ≈5.2 GPa). Besides, the strong chemical connection between unsaturated coordinated Zr⁴⁺ in amorphous structure and PO₄ ^3- greatly strengthen the crystalline-amorphous interface of the repaired enamel to endure the long-time mastication damage. Moreover, these ZrO₂ ceramics provide hydrophilic, electronegative, and smooth surfaces to resist the adhesion and proliferation of cariogenic bacteria. The hybrid amorphous-crystalline interface design with advantages in biomechanical compatibility would promote the evolution of a variety of cutting-edge functional materials for medical and engineering application.