Extraprostatic Uptake of <sup>18</sup>F-Fluciclovine: Differentiation of Nonprostatic Neoplasms From Metastatic Prostate Cancer.
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- Record sourced from PubMed, PMID 31939697.
- Also identified by DOI 10.2214/AJR.19.21894.
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Abstract
<b>OBJECTIVE.</b> Fluciclovine is a synthetic radiolabeled amino acid analog used for imaging of biochemical recurrent prostate cancer. Uptake of fluciclovine is mediated by several amino acid transporters, including alanine-serine-cysteine transporter 2 and large neutral amino acid transporters, which are known to be overexpressed in other malignancies. <b>CONCLUSION.</b> Knowledge of the common patterns of prostate cancer recurrence, in addition to what other neoplasms can show uptake, is critical for accurate study interpretation.
Medical subject headings
- Carboxylic Acids
- Cyclobutanes
- Neoplasm Metastasis
- Neoplasm Recurrence, Local
- Positron Emission Tomography Computed Tomography
- Prostatic Neoplasms