It's Hard to Teach an Old B Cell New Tricks.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31951517.
- Also identified by DOI 10.1016/j.cell.2019.12.019.
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Abstract
Victora and colleagues challenge current perceptions that memory B cells readily participate in secondary germinal center reactions, allowing further modification of specificity upon reactivation. Rather, naïve B cells are the predominant B cell type that populate secondary germinal centers. This work has important basic immunological and translational implications.
Medical subject headings
- Germinal Center
- Immunologic Memory