Iron Deficiency Causes Wrinkles in Host-Commensal Relationships.

Clasen, Sara J; Ley, Ruth E · Cell Metab · 2020

editorial · Level V

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Abstract

Iron is essential for both the host and its resident microbes, resulting in competition under iron-deficient conditions. However, the molecular details underlying this competition are not fully understood. In this issue, Das et al. (2019) describe how a common gut commensal disrupts the host iron regulatory pathway to prevent uptake when iron is scarce.

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