No Zones Left Behind: Democratic Hepatocytes Contribute to Liver Homeostasis and Repair.
editorial · Level V
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- Record sourced from PubMed, PMID 31951586.
- Also identified by DOI 10.1016/j.stem.2019.12.002.
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Abstract
Despite minimal turnover, liver cells possess immense regenerative capacity. Some studies suggest existence of a hepatocyte subset with such unique capabilities. However, in the current issue of Cell Stem Cell, three independent studies (Chen et al., 2020; Matsumoto et al., 2020, and Sun et al., 2020) demonstrate an equitable homeostatic and reparative potential of all hepatocytes, irrespective of their lobular location or ploidy status.
Medical subject headings
- Hepatocytes
- Liver Regeneration