Organoids as Oracles for Precision Medicine in Rectal Cancer.

Kolahi, Kevin S; Nakano, Michitaka; Kuo, Calvin J · Cell Stem Cell · 2020

editorial · Level V

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Abstract

Two recent papers in Cell Stem Cell and Nature Medicine (Yao et al. [2019] and Ganesh et al. [2019]) demonstrate the successful use of rectal cancer patient-derived organoids to predict patient responses to neoadjuvant chemoradiation therapy, paving the way toward a new paradigm for precision medicine.

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