Vagal sensory neurons drive mucous cell metaplasia.
Level V
Where this comes from
- Record sourced from PubMed, PMID 31954778.
- Also identified by DOI 10.1016/j.jaci.2020.01.003 and PMC identifier 8603302.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Airway sensory neuron-produced Substance P heightens allergy-induced goblet cell hyperplasia and hypersecretion of Muc5AC, electrically silencing these overreactive neurons reduced these components of lung type 2 allergic inflammatory response.
Medical subject headings
- Metaplasia
- Mucus
- Sensory Receptor Cells
- Vagus Nerve