Sperm Go to (Transcription) Extremes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 31978338.
- Also identified by DOI 10.1016/j.cell.2019.12.033.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Xia and colleagues show that heritable mutations are kept in check in the male germline partly by "transcriptional scanning," wherein the majority of genes are transcribed and therefore subject to transcription-coupled repair. They provide a new model for understanding the mechanisms of genome surveillance and evolution.
Medical subject headings
- Testis
- Transcription, Genetic