A Single Transcription Factor Drives Toxoplasma gondii Differentiation.

Kochanowsky, Joshua A; Koshy, Anita A · Cell · 2020

basic_science · Level V

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Abstract

Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman et al. have identified a single transcription factor that governs the switch between the lytic and latent forms of Toxoplasma gondii, a parasite that causes a persistent brain infection.

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