Anticoagulation Strategies in the Perioperative Period for Lung Transplant.

Barac, Yaron D; Klapper, Jacob; Pollack, Angela; Poisson, Jessica; Welsby, Ian; Hartwig, M G; Bottiger, Brandi · Ann Thorac Surg · 2020

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Abstract

Patients who are undergoing lung transplantation may require systemic anticoagulation in the perioperative period for various indications at the time of the procedure. Four-factor prothrombin complex concentrate has been approved in the United States to reverse the effects of warfarin for patients requiring urgent surgery. We describe a perioperative anticoagulation strategy with warfarin that is reversed before incision using 4-factor complex concentrate for off-pump lung transplant recipients.

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