Age-Specific Incidence of Influenza A Responds to Change in Virus Subtype Dominance.

Gagnon, Alain; Acosta, Enrique; Miller, Matthew S · Clin Infect Dis · 2020

retrospective_cohort · Level III

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Abstract

When H3N2 replaced H1N1 as the dominant influenza A subtype during the 2018-2019 season, the pattern of age-specific incidence shifted due to the lingering effects of antigenic imprinting. The characteristic shape that imprinting leaves on influenza susceptibility could foster important advances in understanding and predicting the epidemiology of influenza.

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