Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32001482.
- Also identified by DOI 10.1158/1078-0432.CCR-19-3813.
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Abstract
T-cell recognizable p53 hotspot mutations offer opportunities for immunotherapy and immune monitoring. Recognition of p53 mutations by peripheral blood CD8 and CD4 T lymphocytes has been revealed.<i>See related article by Malekzadeh et al., p. 1267</i>.
Medical subject headings
- Antigens, Neoplasm
- Tumor Suppressor Protein p53