Survival of osteosarcoma patients following diagnosis of synchronous skip metastases.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 32021017.
- Also identified by DOI 10.1016/j.jor.2019.10.003 and PMC identifier 6994740.
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Abstract
We aim to investigate the prognostic implications of synchronous skip metastases in osteosarcoma by presenting the largest single centre series to date. Retrospective study of 21 osteosarcoma patients with skip metastases treated between 1983 and 2004. No statistical difference in overall survival was demonstrated when comparing presence of lung metastases to those without (p = 0.859). No statistical difference was found in overall survival according to age group (<18yrs vs >18yrs; p = 0.126), or to percentage chemotherapy-induced bone necrosis (<90% vs >90%; p = 0.056). The presence of skip metastases confers a very poor prognosis as an independent variable. III.