Increased antibiotic duration improves survival of irrigation and debridement after revision total joint arthroplasty.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 32025113.
- Also identified by DOI 10.1016/j.jor.2019.11.020 and PMC identifier 6997659.
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Abstract
We sought to evaluate reoperation-free survival following I&D with modular component exchange of revision total joint arthroplasty (TJA). Of revision TJAs from 2004 to 2012 (n = 4,166), 30 were I&D with modular component exchange after index revision for aseptic indications. Patients with (n = 12) and without (n = 18) reoperation for infection recurrence were analyzed. Reoperation-free survival (60% at mean 4.8 year follow-up) improved with increased duration of antibiotic therapy (p = 0.0185), with maximum benefit at 2 years. At least 2 years of antibiotic therapy should be administered after I&D with modular component exchange for acutely infected revision TJA. Level III, retrospective comparative study.