Playing Favorites: Integrin αvβ5 Mediates Preferential Zika Infection of Neural Stem Cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32032522.
- Also identified by DOI 10.1016/j.stem.2020.01.007.
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Abstract
The molecular basis dictating specificity of Zika virus infection in neural stem cells (NSCs) remains elusive. Two recent papers in Cell Stem Cell (Zhu et al., 2020) and Cell Reports (Wang et al., 2020) identify integrin αvβ5 as an internalization factor that increases susceptibility in NSCs and glioblastoma stem cells.
Medical subject headings
- Glioblastoma
- Neural Stem Cells
- Zika Virus
- Zika Virus Infection