Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32032523.
- Also identified by DOI 10.1016/j.stem.2020.01.011 and PMC identifier 7229643.
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Abstract
Human induced pluripotent stem cells (hiPSCs) provide a potentially unlimited cell source for producing autologous tissue-engineered vascular grafts (TEVGs), which currently suffer from low mechanical strength. In this issue of Cell Stem Cell, Luo et al. (2020) describe optimized culture media and a mechanical stretching regimen to produce hiPSC-derived TEVGs with mechanical behavior similar to that of natural vessels.
Medical subject headings
- Induced Pluripotent Stem Cells