Baseline sputum eosinophil + neutrophil subgroups' clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) cohort.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 32032631.
- Also identified by DOI 10.1016/j.jaci.2020.01.039 and PMC identifier 7343602.
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Abstract
Combined elevated sputum eosinophils+neutrophils in asthma associated with lowest lung function, greater healthcare utilization, and longitudinally, further spirometric loss, implicating cell-cell interactions or overlapping inflammatory pathways while increased eosinophils or neutrophils alone show less effect.
Medical subject headings
- Asthma
- Eosinophils
- Neutrophils
- Sputum