The giant aggressive chondroma: A rare entity, a difficult approach.
case_series · Level IV
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- Record sourced from PubMed, PMID 32042223.
- Also identified by DOI 10.1016/j.jor.2019.09.001 and PMC identifier 7000451.
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Abstract
enchondromas rarely exceed 3-6 cm in long bones. Although the risk of developing secondary chondrosarcoma has been reported up to 4% in solitary lesions, it is not known if size represents a risk factor for transformation. to describe three exceptional cases of enchondromas of the entire femur whereof one dedifferentiated in chondrosarcoma. two patients present stable disease at 5 and 6 years of follow-up; the third, already diagnosed with a dedifferentiated chondrosarcoma, died 14 months after the index surgery for systemic disease. based on these observations, our hypothesis is that lesion size is an important risk factor for malignant transformation.