Preoperative hyponatremia is an independent risk factor for postoperative complications in aseptic revision hip and knee arthroplasty.

Abstract

The purpose of this study is to investigate the relationship between preoperative hyponatremia and postoperative complications in aseptic revision hip and knee arthroplasty. Aseptic revision arthroplasties from 2007 to 2016 were collected using a large, United States database. Patients were stratified into eunatremic and hyponatremic cohorts. Rates of complications were collected and analyzed. 25,517 surgeries were evaluated. Preoperative hyponatremia was independently associated with organ/space infections (OR= 2.316; p<0.001), postoperative blood transfusions (OR= 1.467; p<0.001), pneumonia (OR= 2.05; p =0.002), sepsis (OR= 2.533; p<0.001), extended length-of-stay (OR= 2.221; p<0.001), minor complications (OR= 1.549; p<0.001), wound complications (OR= 1.505; p=0.001), pulmonary complications (OR= 1.72; p=0.007), and sepsis complications (OR= 2.305; p<0.001). Hyponatremia is an independent risk factor for several postoperative complications in aseptic revision hip and knee arthroplasty.