Reverse Sequence Syphilis Screening and Discordant Results in Pregnancy.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32093931.
- Also identified by DOI 10.1016/j.jpeds.2019.11.035.
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Abstract
A "reverse sequence syphilis screening" algorithm is widely used for syphilis testing. This retrospective study showed that most (65%) pregnant women with discordant screening results (treponemal multiplex flow immunoassay IgG+/rapid plasma reagin-) had a nonreactive confirmatory Treponema pallidum-particle agglutination assay, likely indicative of a false-positive reaction.
Medical subject headings
- Pregnancy Complications, Infectious
- Syphilis
- Syphilis Serodiagnosis