Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child.

Lumby, Casper K; Zhao, Lei; Oporto, Macarena; Best, Tim; Tutill, Helena; Shah, Divya; Veys, Paul; Williams, Rachel et al. · Clin Infect Dis · 2020

case_report · Level V

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Abstract

A combination of favipiravir and zanamivir successfully cleared influenza B infection in a child who had undergone bone marrow transplant for X-linked severe combined immunodeficiency, with no recovery of T lymphocytes. Deep sequencing of viral samples illuminated the within-host dynamics of infection, demonstrating the effectiveness of favipiravir in this case.

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