Appetite for Arginine: Metabolic Control of Macrophage Hunger.

Puleston, Daniel J; Pearce, Erika L · Cell Metab · 2020

Level V

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Abstract

Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.

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